کنگره بین المللی زیست فناوری گیاهان دارویی و قارچ های کوهی

صفحه اصلی / سومین کنگره بین المللی و چهارمین همایش ملی زیست فناوری گیاهان دارویی و قارچ های کوهی

The effects of fennel on menstrual bleeding: A systematic review and meta-analysis

نویسندگان :

Nafiseh Ghassab-Abdollahi¹ Mojgan Mirghafourvand² Sanaz Mollazadeh³

1- دانشگاه علوم پزشکی تبریز 2- دانشگاه علوم پزشکی تبریز 3- دانشگاه علوم پزشکی تبریز

کلمات کلیدی :

Fennel, Foeniculum vulgare, Menstrual bleeding, Systematic review

چکیده :

Introduction: Given the widespread use of herbal medicine among women for menstrual problems, it is important to evaluate the effectiveness of fennel on menstrual bleeding. Objectives: the present study was conducted to determine the effect of fennel on the amount (primary outcome) and duration of menstrual bleeding and its side-effects (secondary outcomes). Methods: The databases were searched using MeSH terms. Two authors separately reviewed the inclusion criteria. Quality assessment of randomized clinical trials was conducted using the Cochrane criteria. Results: Six articles were included in the study and four articles entered into the meta-analysis. The results from meta-analysis showed that using fennel caused a significant increase in mean menstrual bleeding in the first cycle after treatment in the intervention group compared to the control (Std. Mean Difference: 0.46; 95% CI: 0.18 to 0.73; P=0.001; I2=9%). However, it had no significant effect on menstrual bleeding in the second cycle after treatment (Mean Difference: 1.44; 95% CI:-5.09 to 7.96; P=0.67; I2=0%). The results of meta-analysis of four articles showed that in the first cycle after treatment, use of fennel increased menstrual bleeding in the intervention group compared to the control, but meta-analysis of two articles showed no significant difference between intervention and control groups in the amount of menstrual bleeding in the second cycle after treatment. Conclusion: Given the poor quality of included studies, conducting clinical trials to determine the effect of fennel on menstrual bleeding appears necessary.