کنگره بین المللی زیست فناوری گیاهان دارویی و قارچ های کوهی

صفحه اصلی / سومین کنگره بین المللی و چهارمین همایش ملی زیست فناوری گیاهان دارویی و قارچ های کوهی

Study of antimicrobial effects of Nanoemulsion of Foeniculum Vulgar essential oil

نویسندگان :

Parisa Kazemi Espili¹ Alireza Yazdinezhad² Somaye Sadighian³ Mehran Mohseni⁴

1- دانشگاه علوم پزشکی زنجان 2- دانشگاه علوم پزشکی زنجان 3- دانشگاه علوم پزشکی زنجان 4- دانشگاه علوم پزشکی زنجان

کلمات کلیدی :

Fennel, essence, nanoemulsion, antimicrobial properties.

چکیده :

The aim of this study was to investigate nanoemulsion of thyme essential oil against some strains of standard bacteria. Thyme essential oil and its synthesized nanoemulsion were used to evaluate the antimicrobial effect against standard bacteria. The nanoemulsion was made from Span 60 and Tween 80 by high energy method with a homogenizer and its stability was evaluated during 3 months. Antimicrobial effect, along with minimum concentration of growth inhibitor (MIC) and minimum bactericidal concentration (MBC) of thyme essential oil on 8 standard bacterial strains was determined by Pure plate method. The size (z-average-nm) results of nanoemulsion made at different times at incubator (37 ° C), refrigerator (4 ° C) and ambient (25 ° C) temperatures showed that the average particle size over time There was a slight increase. The greatest antimicrobial effect was related to Escherichia bacteria. The lowest concentration of essential oils that prevented the growth of 90% of bacteria (MIC) was related to staphylococcus aureus and Micrococcus luteus did not respond. Also, the highest MBC was related to Staphylococcus epidermidis with a minimum lethal concentration of 80 and three bacteria Micrococcus luteus, Bacillus cereus and Pseudomonas aeruginosa did not respond and the highest effect of the synthesized nanoemulsion was on the three bacteria Escherichia coli, and Staphylococcus enterocus. The results showed that thyme essential oil and nanoemulsion made from it had a good antimicrobial effect on most of the studied bacteria.