کنگره بین المللی زیست فناوری گیاهان دارویی و قارچ های کوهی

صفحه اصلی / چهارمین کنگره بین المللی و پنجمین همایش ملی زیست فناوری گیاهان دارویی و قارچ های کوهی

Lepiota metulispora: An imperative source of some secondary metabolites, antibacterial and antioxidant agents

نویسندگان :

Abdul Rehman Niazi¹ Najam-ul-Sehar Afshan² Muniba Shafique³ Alishba Anam⁴

1- university of the punjab, lahore 2- university of the punjab, lahore 3- university of the punjab, lahore 4- university of the punjab, lahore

کلمات کلیدی :

mycochemical screening،secondary metabolites،antibacterial activity،antioxidant potential

چکیده :

The proposed study evaluates the mycochemical composition, antioxidant and antibacterial potential of the Lepiota metulispora. Mycochemical analysis revealed the presence of secondary metabolites such as flavonoids, terpenoids, cardiac glycosides and saponins. The antioxidant potential of ethanolic extract of Lepiota metulispora was assessed using four assays like 2,2-diphenyl-1-picryl-hydrazyl-hydrate (DPPH), 2,2′-azino-bis-3-ethylbenzothiazoline-6-suphonic acid (ABTS), total flavonoid contents (TFC), and total phenolic content (TPC). The DPPH radical scavenging assay showed the maximum percent inhibition of the extract (71.5%±0.145%). Antibacterial activity of mushroom was evaluated against two gram-positive and two gram-negative bacterial strains using agar well diffusion method. Chloroformic extract of Lepiota metullispora exhibited highest antibacterial potential with inhibition zone (29.5±0.289 mm) against Staphylococcus aureus as compared to other bacterial strains. From these findings, it could be assessed that Lepiota metullispora can be used as antibacterial and antioxidant agents to manufacture pharmaceutical drugs and might be used in future.