کنگره بین المللی زیست فناوری گیاهان دارویی و قارچ های کوهی

صفحه اصلی / سومین کنگره بین المللی و چهارمین همایش ملی زیست فناوری گیاهان دارویی و قارچ های کوهی

Antimicrobial activity of thymol as the main monoterpene phenol in some medicinal plants

نویسندگان :

Negin Karami¹ Ali Misaghi²

1- دانشگاه تهران 2- دانشگاه تهران

کلمات کلیدی :

Antibacterial activity, Antifungal activity, Medicinal plants, Thymol

چکیده :

Thymol is the main monoterpene phenol occurring in essential oils isolated from plants belonging to the Lamiaceae family (Thymus, Ocimum, Origanum, and Monarda genera), and other plants such as those belonging to the Verbenaceae, Scrophulariaceae, Ranunculaceae, and Apiaceae families (1). Thymol has been considered as a generally recognized as safe (GRAS) in the Code of Federal Regulations. These essential oils are commercially important-destined chiefly for flavoring ingredients in meat and meat products, drink, and other food products as well as pharmaceutical industries, cosmetics, perfumes, and other home care products (2). Thymol has been shown to possess a wide range of biological activities, including antimicrobial, antioxidant, anti-infalmmatory, modulating of immunity respond and anticarcinogenic properties. It has been indicated that EO obtained from Thymus, Ocimum, Origanum, and Monarda genera (with 67% thymol) had high antimicrobial activity against Escherichia coli, Streptococcus pneumoniae, Bacillus cereus, Clostridium perfringens, Candida albicans, Candida krusei, Acinetobacter lwoffii, and Klebsiella pneumoniae, respectively (3). Thymol cause damage to the Listeria monocytogenes cell membrane and reduce in ATP, ATPase (Na+K+-ATPase and Ca2+-ATPase) activity and respiratory chain complex activity (4).